Conference paper

SUOMI Visa, TREEBY Bradley E., JAROŠ Jiří, SAUNAVAARA Jani, KIVINIEMI Aida and BLANCO Roberto. The Effect of Tissue Physiological Variablity on Transurethral Ultrasound Therapy of the Prostate. In: Proceedings of 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). Honolulu, HI: Institute of Electrical and Electronics Engineers, 2018, pp. 5701-5704. ISBN 978-1-5386-3646-6. Available from: https://ieeexplore.ieee.org/document/8513548
Publication language:english
Original title:The Effect of Tissue Physiological Variablity on Transurethral Ultrasound Therapy of the Prostate
Title (cs):Zkoumání vlivu fyziologických vlastností tkáně na transuretální ultrazvukovou terpaii prostaty
Pages:5701-5704
Proceedings:Proceedings of 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Conference:40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Place:Honolulu, HI, US
Year:2018
URL:https://ieeexplore.ieee.org/document/8513548
ISBN:978-1-5386-3646-6
DOI:10.1109/EMBC.2018.8513548
Publisher:Institute of Electrical and Electronics Engineers
Keywords
Ultrasonic imaging, Thermal conductivity, Heating systems, Conductivity, Computational modeling, Attenuation, Probes
Annotation
Therapeutic ultrasound is an established modality which can be used for minimally invasive treatment of prostate cancer. Computational simulation models were used to study the effect of natural physiological variations in tissue parameters on the efficacy of therapeutic ultrasound treatment in the prostate. The simulations were conducted on a clinical ultrasound therapy system using patient computed tomography (CT) data.
The values of attenuation, perfusion, specific heat capacity and thermal conductivity were changed within their biological ranges to determine their effect on peak temperature and thermal dose volume. Increased attenuation was found to have the biggest effect on peak temperature with a 6.9% rise. The smallest effect was seen with perfusion with 0.2% variation in peak temperature. Thermal dose was mostly affected by specific heat capacity which showed a 20.7% increase in volume
with reduced heat capacity. Thermal conductivity had the smallest effect on thermal dose with up to 2.1% increase in the volume with reduced thermal conductivity. These results can be used to estimate the expected interpatient variation during the therapeutic ultrasound treatment of the prostate.
BibTeX:
@INPROCEEDINGS{
   author = {Visa Suomi and E. Bradley Treeby and
	Ji{\v{r}}{\'{i}} Jaro{\v{s}} and Jani Saunavaara
	and Aida Kiviniemi and Roberto Blanco},
   title = {The Effect of Tissue Physiological Variablity on
	Transurethral Ultrasound Therapy of the Prostate},
   pages = {5701--5704},
   booktitle = {Proceedings of 40th Annual International Conference of the
	IEEE Engineering in Medicine and Biology Society (EMBC)},
   year = {2018},
   location = {Honolulu, HI, US},
   publisher = {Institute of Electrical and Electronics Engineers},
   ISBN = {978-1-5386-3646-6},
   doi = {10.1109/EMBC.2018.8513548},
   language = {english},
   url = {http://www.fit.vutbr.cz/research/view_pub.php?id=11636}
}

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