Conference paper

VOGEL Ivan, OČENÁŠEK Pavel and ZEDEK František. Computational molecular evolution - from mathematical models to novel distance metric based on intra-group analysis. In: EDS '11 IMAPS CS International Conference Proceedings. Brno: Brno University of Technology, 2011, pp. 264-269. ISBN 978-80-214-4303-7.
Publication language:english
Original title:Computational molecular evolution - from mathematical models to novel distance metric based on intra-group analysis
Title (cs):Výpočtová molekulární evoluce - od matematických modelů k novým vzdálenostním metrikám pracujících na základě vnitroskupinové analýzy
Pages:264-269
Proceedings:EDS '11 IMAPS CS International Conference Proceedings
Conference:18th Electronic Devices and Systems IMAPS CS International Conference
Place:Brno, CZ
Year:2011
ISBN:978-80-214-4303-7
Publisher:Brno University of Technology
Keywords
phylogeny, intra-group analysis, substitution model, Markov chains
Annotation
In the proposed paper we analyse and discuss the molecular evolution from the point of view of mathematical analysis and statistics. Some characteristics of distance-based algorithms for phylogenetic inference are depicted. We furthermore use knowledge of mathematical models to design a modified algorithm for phylogenetic tree reconstruction. We implement the presented methods in the form of a simple phylogenetic library, briefly report about results of our case study and finally show a way for building a web interface for biological purposes through Mobyle portal. Finally, we draw a conclusion and discuss possible future work on the project.
BibTeX:
@INPROCEEDINGS{
   author = {Ivan Vogel and Pavel O{\v{c}}en{\'{a}}{\v{s}}ek and
	Franti{\v{s}}ek Zedek},
   title = {Computational molecular evolution - from mathematical models
	to novel distance metric based on intra-group analysis},
   pages = {264--269},
   booktitle = {EDS '11 IMAPS CS International Conference Proceedings},
   year = {2011},
   location = {Brno, CZ},
   publisher = {Brno University of Technology},
   ISBN = {978-80-214-4303-7},
   language = {english},
   url = {http://www.fit.vutbr.cz/research/view_pub.php.en.iso-8859-2?id=9549}
}

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