Journal article

BRÁZDIL Milan, DOBŠÍK Martin, PAŽOURKOVÁ Marta, KRUPA Petr and REKTOR Ivan. Význam funkční magnetické rezonance pro hodnocení kognitivních pochodů v lidském mozku. Lokalizace "oddball" úkolem aktivovaných neuronálních populací. Česká a slovenská neurologie a neurochirurgie. 2002, vol. 2002, no. 5, pp. 20-30. ISSN 1210-7859.
Publication language:czech
Original title:Význam funkční magnetické rezonance pro hodnocení kognitivních pochodů v lidském mozku. Lokalizace "oddball" úkolem aktivovaných neuronálních populací.
Title (en):The Role of fMRI in Evaluation of Congnitive Function of Human Brain. Localisation of Activated Neuronal Population using `oddball` task
Journal:Česká a slovenská neurologie a neurochirurgie, Vol. 2002, No. 5, CZ
Oddball; event-related fMRI; SPM; P3 genesis
The functional MRI method underwent rapid development during the last decade. It maps neuronal activation indirectlty by examining cortical haemodynamic changes. We still do not know its exact relation to study of cognitive function. We present "event-related" functional MR (efMRI) study of auditory "oddball" paradigma in 10 healthy volunteers in this paper. We compared results of present efMRI study with results of our previous ERP study to evaluate the measure of equality between regions with significantly different haemodynamic response to frequent and target stimuly, and known position of intracerebral P3 generators. Both methods revealed activation of many regions, especially in parietal and frontal lobe (lobulus parietalis superior, inferior, gyrus supramarginalis, gyrus cinguli, lateral prefrontal cortex, gyrus temporalis superior and thalamus). Haemodynamic activation in most of these structures was right lateralized in accordance to todays knowledge. On the contrary, not the presented study nor any other previous study reveal the expected haemodynamic response in most significant P3 generator - amygdalohyppocampal complex. Even if the efMRI method is very useful in recognition of neurocognitive corelates of mental processes, the method itself is not able to find complete map of activated brain areas during cognitive function. This may be caused due to incomplete ability of the efMRI metod in capturing very short transient changes in neuronal populations. Thus It is still necessary to consider efMRI as complementar method and evaluate it results very carefully.
   author = {Milan Br{\'{a}}zdil and Martin Dob{\v{s}}{\'{i}}k and Marta
	Pa{\v{z}}ourkov{\'{a}} and Petr Krupa and Ivan Rektor},
   title = {V{\'{y}}znam funk{\v{c}}n{\'{i}} magnetick{\'{e}} rezonance
	pro hodnocen{\'{i}} kognitivn{\'{i}}ch pochod{\r{u}} v
	lidsk{\'{e}}m mozku. Lokalizace "oddball"
	{\'{u}}kolem aktivovan{\'{y}}ch neuron{\'{a}}ln{\'{i}}ch
   pages = {20--30},
   journal = {{\v{C}}esk{\'{a}} a slovensk{\'{a}} neurologie a
   volume = {2002},
   number = {5},
   year = {2002},
   ISSN = {1210-7859},
   language = {czech},
   url = {}

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