Monograph

BURGETOVÁ Ivana, ZENDULKA Jaroslav and LEXA Matej. Clustering Techniques for Protein Fragments Analysis. Brno: Faculty of Information Technology BUT, 2010. ISBN 978-80-214-4207-8.
Publication language:english
Original title:Clustering Techniques for Protein Fragments Analysis
Title (cs):Shlukovací techniky pro analýzu proteinových fragmentů
Pages:102
Place:Brno, CZ
Year:2010
ISBN:978-80-214-4207-8
Publisher:Faculty of Information Technology BUT
Keywords
Protein structure, Protein Data Bank, clustering, density-based clustering, sequence-structure relationships in proteins, clustering of protein fragments, protein structure prediction, sequence-structures fragments search.
Annotation
This book presents a novel method for clustering of protein substructures that we developed in order to study the relationships between protein sequences and their structure. We show some properties of this method and the experimental results obtained by analyzing real data from PDB (Protein Data Bank). Furthermore, we present the results of the comparison of our method and the most commonly used methods for clustering of protein structures. The main advantage of our method is its high efficiency and scalability, which are key factors for analyzing large data sets. Finally, we propose a procedure for finding sequence profiles that tend to occur in more than one structural conformation but the number of their structural conformations is limited. This procedure is based on our method for protein substructure clustering.
BibTeX:
@BOOK{
   author = {Ivana Burgetov{\'{a}} and Jaroslav Zendulka and Matej Lexa},
   title = {Clustering Techniques for Protein Fragments Analysis},
   pages = {102},
   year = {2010},
   location = {Brno, CZ},
   publisher = {Faculty of Information Technology BUT},
   ISBN = {978-80-214-4207-8},
   language = {english},
   url = {http://www.fit.vutbr.cz/research/view_pub.php?id=9504}
}

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