Thesis Details
Bioinformatický nástroj pro anotaci transposonů
This thesis provides theoretical resources for the design of a new bioinformatics tool for transposon annotation with focus on their additional structural elements. There is a biological description of transposons, the mobile elements in DNA, their classification and structure. It further deals with the overview and classification of available transposon identification and annotation bioinformatics tools, description of function and implementation of a select few. Next we state the scheme of a new bioinformatics tool for LTR retrotransposon identification and annotation with a focus on extra ORFs and tandem repeats. The functionality of this new tool was tested on the A. thaliana genome. We identified 95 groups of conserved extra ORFs and 10 groups of conserved tandem repeats.
transposons, satellite DNA, bioinformatics, annotation, extra ORF, tandem repeats, LTR retrotransposons
Burgetová Ivana, Ing., Ph.D. (DIFS FIT BUT), člen
Horák Aleš, doc. RNDr., Ph.D. (FI MUNI), člen
Martínek Tomáš, doc. Ing., Ph.D. (DCSY FIT BUT), člen
Rogalewicz Adam, doc. Mgr., Ph.D. (DITS FIT BUT), člen
Zbořil František, doc. Ing., Ph.D. (DITS FIT BUT), člen
@mastersthesis{FITMT19833, author = "Michal Jen\v{c}o", type = "Master's thesis", title = "Bioinformatick\'{y} n\'{a}stroj pro anotaci transposon\r{u}", school = "Brno University of Technology, Faculty of Information Technology", year = 2017, location = "Brno, CZ", language = "czech", url = "https://www.fit.vut.cz/study/thesis/19833/" }