Title:

Bioinformatics

Code:IV108
Ac.Year:2018/2019
Term:Winter
Curriculums:
ProgrammeFieldYearDuty
CSE-PHD-4DVI4-Elective
Language of Instruction:Czech
Completion:examination (verbal)
Type of
instruction:
Hour/semLecturesSeminar
Exercises
Laboratory
Exercises
Computer
Exercises
Other
Hours:1313000
 ExamsTestsExercisesLaboratoriesOther
Points:1000000
Guarantor:Lexa Matej, Ing., Ph.D. (FI)
Lecturer:Lexa Matej, Ing., Ph.D. (FI)
Faculty:Faculty of Informatics MU
 
Description:
  An advanced course in bioinformatics (lecture and computer lab) building upon elementary mol.biology and/or bioinformatics courses.
Syllabus of lectures:
 1. Biological language (sequence segmentation, information-statistical analysis of biological sequences)
2. Pattern matching (algoritms based on filtration and suffix arrays)
3. Heuristic algorithms for similarity searching in biological sequences (BLAST, BLAT, Pattern Hunter)
4. Regular expressions in bioinformatics
5. Algorithms for analysis and prediction of structural data (secondary strukture, contacts inb proteins, domain identification)
6. Algorithms for analysis and prediction of structural data (3D structure, structural comparisons)
7. Working with molecular structures in Pymol
8. New methods of DNA sequencing
9. Genome assembly and other operations on short nucleic acid sequences
10. Prediction of melting temperature in DNA and other nucleic acids (program mfold)
11. RNA secondary structure
12. DNA computing
13. Comparative genomics of human (analysis of scientific papers)
 

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