Product Details

pqsfinder: an R/Bioconductor package for identification of potential quadruplex forming sequences

Created: 2016

Czech title
pqsfinder: R/Bioconductor balíček pro identifikaci sekvencí tvořících kvadruplexy
Type
software
License
optional - free
Authors
Hon Jiří, Ing., Ph.D. (DIFS FIT BUT)
Lexa Matej, Ing., Ph.D. (FI MUNI)
Martínek Tomáš, doc. Ing., Ph.D. (DCSY FIT BUT)
Zendulka Jaroslav, doc. Ing., CSc. (DIFS FIT BUT)
Keywords

G-quadruplex; quadruplex; DNA; R; Bioconductor; pattern matching; searching; annotation

Description

The main functionality of the this package is to detect DNA sequence patterns that are likely to fold into an intramolecular G-quadruplex (G4). Unlike many other approaches, this package is able to detect sequences responsible for G4s folded from imperfect G-runs containing bulges or mismatches and as such is more sensitive than competing algorithms.

Location
Licence

Free software under the terms of BSD license (see http://www.opensource.org/licenses/bsd-license.php).

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